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Postdoctoral Research Fellow - Time-Resolved Crystallography Development
Salary:
60.00 - 80.00
Posted:
01-03-2025
Category:
Biology, Biotech Chemistry
Melbourne,
Job Description
Postdoctoral Research Fellow - Time-Resolved Crystallography Development Join the Swinburne Department of Physics and Astronomy About the Role The Department of Physics and Astronomy at Swinburne University is seeking a highly motivated Postdoctoral Research Fellow to join Assoc. Prof. Nadia Zatsepin’s group in the Optical Sciences Centre to establish a new lab focused on method development in serial crystallography and grow X-ray free-electron laser science in Australia.The focus will be two-fold: developing serial crystallography at the Australia Synchrotron and developing time-resolved serial crystallography to capture the structural dynamics of E. coli disulfide bond-forming enzyme A (DsbA) during its enzymatic cycle. DsbA plays a crucial role in oxidative protein folding and is a potential drug target to combat antimicrobial resistance. The position offers a unique opportunity to contribute to both technical advancements in crystallographic methodology as well as deepening our understanding of the molecular mechanisms governing disulfide bond formation.The ideal candidate will have experience in protein crystallization, X-ray crystallography experiments and data analysis, with a strong interest in serial and time-resolved crystallography. They should have excellent organisational, project management, and communication skills, as well as experience with student supervision and mentoring. Experience in setting up a crystallization laboratory would be highly valued.The appointee is expected to communicate research results in international refereed journals and conferences, contribute to beamtime and grant funding proposal writing, mentor and co-supervise undergraduate, Masters and PhD students, work with minimal supervision, as well as manage the crystallisation laboratory space independently. If you are interested in cutting-edge method development in biophysics, molecular mechanisms, and advancing drug discovery, we encourage you to apply. About You To be suitable for this role you will need to have experience in the below key accountabilities: Strong background in macromolecular crystallography, ideally with experience in time-resolved or serial crystallography. Proficiency in crystallographic data analysis software (e.g., CrystFEL, Phenix, CCP4, XDS). Record of publications, conference presentations and/or technical contributions demonstrating research capabilities. Strong analytical skills and ability to communicate results and interpretation clearly to an interdisciplinary audience. Qualifications PhD in crystallography, structural biology, biophysics, biochemistry, X-ray physics or similar. To Apply Please submit your CV and cover letter (2 pg) briefly addressing the key selection criteria for this position.Applications Close: Friday 28th March 2025, 11pm #J-18808-Ljbffr
Job Details
Salary: 60.00 - 80.00
Posted: 01-03-2025
Category: Biology, Biotech Chemistry
Melbourne,
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